Historic region, southwestern France. The Guyenne region corresponds to the modern département of Gironde and to most of the départements of Lot-et-Garonne, Dordogne, Lot, and Aveyron. An old duchy whose capital was at Bordeaux, it was near the Garonne and Dordogne rivers. From Roman times until the Middle Ages it was part of the region of Aquitaine. Under English control during much of the later Middle Ages, Guyenne was retaken by the French at the beginning of the Hundred Years’ War, but in 1360 it was restored, with Aquitaine, to the English. France later reconquered the area, and from the 17th century until 1789 Guyenne was part of the French gouvernement of Guienne and Gascony. For more information on Guyenne, visit Britannica.com.